吴刚
教育经历
浙江大学（原浙江农业大学）园艺系，获学士学位;
浙江大学生物物理国家重点学科，获理学博士学位。
工作经历
北京大学生命科学学院蛋白质工程与植物基因工程国家重点实验室北大-耶鲁植物分子生物学中心从事博士后研究，合作导师为李毅教授;
美国宾夕法尼亚大学（University of Pennsylvania）生物系从事博士后研究，任研究科学家，合作导师为美国科学院院士Scott Poethig 教授;
浙江农林大学农业与食品科学学院教授。
研究方向
植物遗传、发育分子生物学、土壤污染物植物修复
实验室主要以拟南芥、园艺植物和林木为研究对象，采用遗传学、分子生物学、生理生化、基因组学等方法来研究微小 RNA-miR156 参与调控植物营养生长(植物童期形成)以及植物性型分化的分子机制，为缩短植物童期、改良植物生长发育提供理论依据。实验室同时开展遗传改良植物来提高对重金属镉及其它污染物积累的研究。
所任职务与学术兼职
浙江农林大学农业与食品科学学院院长
浙江农林大学学术委员会委员
吉林大学植物科学学院兼职教授、博士生导师
青岛农业大学兼职教授
中国生物化学和分子生物学农业分会理事
主持或参与项目
已主持多个国家基金面上项目、浙江省杰出青年基金项目、浙江省基金重点项目
代表性论文
第一作者文章
1. Gang Wu, Mee Yeon Park, Susan Conway, Jia-wei Wang, Detlef Weigel, and R. Scott Poethig (2009) The sequential action of miR156 and miR172 regulates developmental timing in Arabidopsis. Cell 138 (4): 750-759
2. Gang Wu, Wan-ching Lin, Tengbo Huang, R. Scott Poethig, Patricia S. Springer, Randall A. Kerstetter (2008) KANADI1 regulates abaxial-abaxial polarity in Arabidopsis by directly repressing the transcription of ASYMMETRIC LEAVES2. PNAS 105(42): 16393-16398
3. Gang Wu and R. Scott. Poethig (2006) Temporal regulation of shoot development in Arabidopsis by miR156 and its target SPL3. Development 133: 3539-3547
4. Gang Wu, Gabrielle Rossidivito, Tieqiang Hu, Yosef Berlyand，and R. Scott Poethig (2015) Traffic Lines: New Tools for Genetic Analysis in Arabidopsis thaliana. Genetics 200:35-45
5. Gang Wu (2013) Plant MicroRNAs and Development. Journal of Genetics and Genomics 40:217-230
6. Gang Wu, Hairui Cui, Gongyin Ye, Yingwu Xia, Sardana Ravinder, Xiongying Cheng, Yi Li, Altosaar Illimar & Qingyao Shu (2002) Inheritance and expression of the cry1Ab gene in Bt (Bacillus thuringiensis) transgenic rice. Theoretical and Applied Genetics 104(4): 727-734
通讯作者及合作者文章(*通讯作者)
1.Xiang Wang, Xia Song, Huaiqi Miao, Shengjun Feng*, and Gang Wu*(2024)Natural variation in CYCLIC NUCLEOTIDE-GATED ION CHANNEL 4 reveals a novel role of calcium signaling in vegetative phase change in Arabidopsis. New Phytologist doi:10.1111/nph.19498
2.Bingying Zhou, Qing Luo, Yanghui Shen, Liang Wei,Xia Song, Hangqian Liao, Lan Ni, TaoShen, Hanjun You, Xinglin Dou, Mingyi Jiang, Shengjun Feng*, and Gang Wu*(2023). Coordinated regulation of vegetative phase change by brassinosteroids and the age pathway in Arabidopsis. Nature Communications,14:2608,https//doi.org/10.1038/s41467-023-38207-z
3.Xiang Wang, Huaiqi Miao, Caijia Lv, Gang Wu*(2023) Genome wide association study identifies a novel BMI1A QTL allele that confers FLC expression diversity in Arabidopsis thaliana. Journal of Experimental Botany erad120,https://doi.org/10.1093/jxb/erad120
4. Huihui Fang*, Yuke Shao, and Gang Wu* (2021) Reprogramming of histone H3 lysine methylation during plant sexual reproduction. Frontiers in Plant Science, https://doi: 10.3389/fpls.2021.782450
5. Changkui Guo, Youqi Jiang, Min Shi, Xi Wu, and Gang Wu* (2021) ABI5 acts downstream of miR159 to delay vegetative phase change in Arabidopsis. New Phytologist 231(1):339-350
6. Jingtao Nie, Huaseng Wang,Wanlu Zhang, Xue Teng, Chao Yu, Run Cai, Gang Wu* (2021) Characterization of lncRNAs and mRNAs involved in powdery mildew resistance in cucumber. Phytopathology doi: 10.1094/PHYTO-11-20-0521-R
7.Lu Zhang, Han Ding, Hailing Jiang, Huasen Wang, Kexin Chen, Jinju Duan, Shengjun Feng*, Gang Wu* (2020) Regulation of cadmium tolerance and accumulation by miR156 in Arabidopsis. Chemosphere 242: 125168
8.Yunmin Xu, Zhiyuan Qian, Bingying Zhou, Gang Wu* (2019) Age-dependent heteroblastic development of leaf hairs in Arabidopsis. New Phytologist 224(2):741-748
9. Hui Zhang, Lu Zhang, Junyou Han, Zhiyuan Qian, Bingying Zhou, Yunmin Xu*, and Gang Wu* (2019) The nuclear localization signal is required for the function of Squamosa Promoter Binding Protein-like Gene 9 to promote vegetative phase change in Arabidopsis. Plant Molecular Biology 100:571-578
10. Yafei Ge, Junyou Han, Guoxin Zhou, Yunmin Xu, Yue Ding, Ming Shi, Changkui Guo*, and Gang Wu*(2018) Silencing of miR156 confers enhanced resistance to brown planthopper in rice. Planta 248:813–826
11. Yunmin Xu, Lu Zhang, and Gang Wu* (2018) Epigenetic regulation of juvenile-to-adult transition in plants. Frontiers in Plant Science (invited review) i.9:1048.doi:10.3389/fpls.2018.01048
12. Changkui Guo, Yunmin Xu, Min Shi,Yongmin Lai, Xi Wu, Zhujun Zhu, Huasen Wang, R Scott Poethig, and Gang Wu* (2017) Repression of miR156 by miR159 regulates the timing of the juvenile-to-adult transition in Arabidopsis. Plant Cell 29(6):1293-1304
13. Yunmin Xu, Changkui Guo, Bingying Zhou, Chenlong Li, Huaseng Wang, Ben Zheng, Han Ding, Zhujun Zhu, Angela Peragine, Yuhai Cui, Scott Poethig, and Gang Wu* (2016) Regulation of vegetative phase change by SWI2/SNF2 chromatin remodeling ATPase BRAHMA. Plant Physiology 172: 2416-2428
14. Mingli Xu，Tieqiang Hu, Jianfei Zhao, MeeYeon Park, Keith Earley, Gang Wu Li Yang, R. Scott Poethig (2016) Developmental Functions of miR156-Regulated SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) Genes in Arabidopsis thaliana. PLOS Genetics DOI:10.1371/journal.pgen.1006263
15. Shengjun Feng, Yunmin Xu, Changkui Guo, Jirong Zheng, Bingying Zhou, Yuting Zhang, Yue Ding, Lu Zhang, Zhujun Zhu, Huasen Wang, and Gang Wu (2016) Modulation of miR156 to identify traits associated with vegetative phase change in tobacco (Nicotiana tabacum L.). Journal of Experimental Botany doi:10.1093/jxb/erv551
16. Li Yang, Gang Wu, R. Scott Poethig (2012) Mutations in the GW-protein SUO reveal a developmental function for miRNA-mediated translational repression in Arabidopsis. PNAS 109: 315-320
17. Meeyeon Park, Gang Wu, Alfredo Gonzalez-Sulser, Herve Vaucheret, and R. Scott Poethig (2005) Nuclear processing and export of microRNAs in Arabidopsis. PNAS 102(9): 3691-3696
18. Feng Zhou, Gang Wu, Wulan Deng, Yingying Pu, Chunhong Wei, Yi Li (2007) Interaction of rice dwarf virus outer capsid P8 protein with rice glycolate oxidase mediates relocalization of P8. FEBS Letters 581: 34-40
19. Angela Peragine, Manabu Yoshikawa, Gang Wu, Heidi L. Albrecht, R. Scott Poethig (2004) SGS3 and SGS2/SD1/RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis. Genes & Development 18:2368-2379
20. Michael Smith, Matthew Willmann, Gang Wu, Barbara Moeller, Dolf Weijers and R. Scott Poethig. (2009) Cyclophilin 40 is required for microRNA activity in Arabidopsis. PNAS 106: 5424-5429
21. Christine Hunter, Matthew Willmann, Gang Wu, M. Gutierrez-Nava and R. Scott. Poethig (2006) Trans-acting siRNA mediated repression of ETTIN and ARF4 regulates heteroblasty in Arabidopsis. Development 133:2973-2981
22. Ayoko Yamaguchi, Minnfeng Wu, Li Yang, Gang Wu, R. Scott Poethig, Doris Wagner (2009) The microRNA-reguated SBP-box transcription factor SPL3 is a direct transcriptional activator of LEAFY, FRUITFULL and APETALA1. Developmental Cell 17(2): 268-278
23. Yi Li, Yi M. Bao, Chun H. Wei,Zhen S. Kang, Yong W. Zhong, Peng Mao, Gang Wu, Zhang L. Chen, Joachim Schiemann, and Richard S. Nelson (2004) Rice dwarf phytoreovirus segment S6-encoded nonstructural protein has a cell-to-cell movement function. Journal of Virology 78(10): 5382-5389
24. Poethig, R. S., A. Peragine, M. Yoshikawa, C. Hunter, M. Willmann and G. Wu (2006) The function of RNAi in plant development. Cold Spring Harbor Symp. Quant. Biol. 71: 165-170
办公地点：浙江农林大学学15-108
Email：wugang @zafu.edu.cn
