方慧慧，女，副教授，硕士生导师，理学博士。2017年毕业于山西大学植物学专业，获山西省优秀博士论文。2017-2019年至南方科技大学与华南农业大学联合培养博士后，荣获深圳市高层次专业人才称号。2020年至今任浙江农林大学园艺学院专任教师。担任《田间试验与统计分析》、《生物统计与试验设计》、《试验统计与数据分析》、《园艺专业竞赛培训》、《大学生竞赛与创新实践》等课程主讲，曾获校级青年教师教学竞赛一等奖（2025年）。主要研究方向：①蔬菜作物重要农艺性状及逆境响应的调控位点挖掘及功能解析；②植物气体信号分子功能及信号转导机制解析。以第一作者及通讯作者在Plant Journal、Horticulture Research、Science Bulletin、Plant Science、Plant Cell & Physiology、Plant Physiology and Biochemistry等期刊发表学术论文10余篇，担任Horticulture Research、Plant Science等杂志审稿专家，担任Plant Hormones期刊青年编委。

主持项目：

1. 国家自然科学基金青年基金，miR156调控气体信号分子H₂S产生诱导番茄气孔关闭的分子机理，2022.1-2024.12，主持；

2. 浙江省自然科学基金，植物胚乳发育过程中non-CG甲基化调控的分子机制探究，2021.1-2023.12，主持；

3. 中国博士后科学基金第65批面上资助，植物VIM5蛋白调控胚乳non-CG甲基化的作用机制探究，主持；

4. 科技特派员项目，古塘下村桃园绿色优质栽培技术体系建立与示范推广，2024.9-2026.11，主持；

代表性论文：

1. Fang H#, Zhang X#, Xu, Y#, Chen W, Zheng K, Zhao W, Zang Y, Zang Y* (2026) H₂S generated by L-cysteine desulfhydrase (SlLCD1) enhances heat tolerance in tomato via antioxidant capacity and stomatal modulation. Horticulture research, 13(7), uhag090. https://doi.org/10.1093/hr/uhag090

2. Fang H#*, Zheng K#, Zang Y#, Xu Y, Zhang X, Zhao W, Chen W, Wang Y, Lu M, Zang, Y* (2026) Transcriptomic profiling of the response to high night-time temperature stress in tomato leaves. Plant & Cell Physiology, 67(8), 1368-1384.

3. Wang Z#, Chen F#, Xu Y, Zang Y, Chen W, Zang Y*, Fang H* (2026) Functions and interactions of important sulfur-containing metabolites in plant development and stress responses. Plant & Cell Physiology, 67(9), 1461-1472.

4. Fang H, Chen W, Xing K, Xu L, Wu J, Huang Y, Pei Y, Zang Y* (2025) Hydrogen sulfide generated by L-cysteine desulfhydrase 1 enhances plant basal thermotolerance through the regulation of stomatal behavior and the promotion of photosynthetic efficiency. Plant Science, 361, 112805.

5. Fang H#, Zhang X#, Chen W#, Xu L, Yao J, Pei Y, Zang Y* (2024) Dynamic changes of endogenous H₂S generation during responding to developmental and environmental signals in Solanum lycopersicum L., Scientia Horticulturae, 335,113346.

6. Fang H, Zang Y* (2024) An overview of analytical methods for detecting endogenous hydrogen sulfide (H₂S) in plants. Journal of Plant Physiology, 19(302): 154315.

7. Fang H#*, Liu R#, Yu Z#, Shao Y, Wu G, Pei Y* (2022) Gasotransmitter H₂S accelerates seed germination via activating AOX mediated cyanide-resistant respiration pathway. Plant Physiology and Biochemistry, 1(190): 193-202.

8. Fang H#, Yu Z#, Xing K#, Zhou L, Shao Y, Zhang X, Pei Y, Zhang L* (2023) Transcriptomic analysis reveals the functions of H₂S as a gasotransmitter independently of Cys in Arabidopsis. Frontiers in Plant Science, 14:1184991.

9. Fang H#, Shao Y#, Wu G* (2021) Reprogramming of histone h3 lysine methylation during plant sexual reproduction. Frontiers in Plant Science, 12:782450.

10. Fang H#, Liu Z, Long Y, Jin Z, Zhang L, Liu D, Zhai J*, Pei Y* (2017). The Ca²⁺/CaM2 binding transcription factor TGA3 elevates LCD expression and H₂S production to bolster Cr⁶⁺ tolerance in Arabidopsis. The Plant Journal, 91(6):1038-1050.

11. Fang H#, Liu Z, Jin Z, Zhang L, Liu Di, Pei Y* (2016) An emphasis of hydrogen sulfide-cysteine cycle on enhancing the tolerance to chromium stress in Arabidopsis. Environmental Pollution, 870-877.

12. Liu Z#, Fang H#, Pei Y*, Jin Z, Zhang L, Liu D (2015) WRKY transcription factors down-regulate the expression of H₂S-generating genes, LCD, and DES1, in Arabidopsis thaliana. Science Bulletin, 995-1001. (Co-first author)

13. Fang H#, Jing T#, Liu Z, Zhang L, Jin Z, Pei Y* (2014). Hydrogen sulfide interacts with calcium signaling to enhance the chromium tolerance in Setaria italica, Cell Calcium, 56(6), 472-481.

14. Jia J#, Lu W#, Liu B, Fang H, Yu Y, et al., Zhai J* (2022). An atlas of plant full-length RNA reveals tissue-specific and monocots-dicots conserved regulation of poly(A) tail length, Nature Plants, 10.1038.

15. Pei Y, Jin Z, Liu Z, Fang H, et al, in Gasotransmitters, ed. R. Wang, The Royal Society of Chemistry, 2018, ch. 9, pp. 235-282. Chapter 9. Gasotransmitters in Plants, http://dx.doi.org/10.1039/9781788013000.（排名第四）。

教育教学：

1. 获浙江农林大学青年教师教学大赛一等奖，2025；

2. 指导研究生完成浙江省教育厅一般科研项目（结题），2025；

3. 指导学生参加第九届全国大学生生命科学竞赛（一类竞赛）获得二等奖，2024；

4. 指导学生获得本科生优秀毕业论文，2024；

5. 指导学生完成创新创业项目：国家级1项、省级2项、校级2项；

6. 获课程思政育人大纲优秀案例二等奖，2022;

办公地点：学18-417

Email: fanghh@zafu.edu.cn